A Pyrrolidine Functionalized Poly[(Ethylene Glycol) Methacrylate] Resin as a Heterogeneous Catalyst for Aqueous Aldol Reactions

The development of a performant aminated catalyst for aldol condensations requires the combined tuning active site, support and solvent system. For this purpose, pyrrolidine group was immobilized on swellable polymer resin. Favorable interactions between water (in its role as solvent) resulted in turnover frequency (TOF) amounting to 3.0 ± 1.5 × 10−3 s−1, despite potential inhibition sites by formation iminium species. affinity poly[(ethylene glycol) methacrylate] efficient swelling catalytic material, which shown be key observed performance.